VCF (Variant Name Format) is a textual content file format for storing genetic variants. It’s generally utilized in bioinformatics to characterize the outcomes of variant calling, which is the method of figuring out variations between two or extra DNA sequences. VCF recordsdata can be utilized for quite a lot of functions, together with variant annotation, filtering, and evaluation.
VCF recordsdata are sometimes tab-delimited and have a header line that describes the columns. The primary column comprises the chromosome identify, the second column comprises the place of the variant, and the third column comprises the reference allele. The remaining columns comprise the alternate alleles and different details about the variant, reminiscent of the standard of the decision and the genotype of the person.
